Organic chemistry is an important basic course for chemistry and chemical engineering majors. It is also one of the compulsory courses in life science, pharmacy, medicine and environmental science. The basic knowledge of organic chemistry includes the theoretical basis, basic structure, naming and properties of organic compounds, as well as the internal relationship between structure and properties. With the continuous progress and development of science and technology, the contents involved in organic chemistry are constantly enriched and updated. Therefore, the content setting of this course appropriately combines the frontier and development trend of the discipline, so as to keep pace with the times. Firstly, this course briefly introduces the basic bonding theory of organic chemistry, covalent bond properties, the classification and naming of organic compounds, and the relationship between weak interactions between organic molecules and physical properties. The phenomenon of isomerization of organic compounds was systematically introduced. Then, based on the acid change of organic compounds, the effects of substituent effects on the electron cloud distribution and chemical properties of organic molecules were discussed. On the basis of introducing the internal relationship between the structure and physicochemical properties of organic compounds, the focus of the course shifted to the introduction of the properties of organic compounds, preparation methods and important reactions involving different functional groups. Taking organic functional groups as the main line, the reaction characteristics of different functional groups and the influence of substituents on the reactivity of these functional groups were introduced. The content mainly involves saturated hydrocarbons, olefins and alkynes, aromatics, halogenated hydrocarbons, oxygenated organic compounds (alcohols, phenols, ethers, aldehydes, ketones, carboxylic acids and derivatives), nitrogen-containing organic compounds, aromatic heterocyclic compounds and bioactive macromolecules (sugars, lipid compounds, amino acids and proteins, nucleic acids). The teaching goal of this course is to enable students to firmly grasp the basic theoretical knowledge of organic chemistry, cultivate students' ability to use this knowledge to solve relevant problems, cultivate their ability to renew knowledge and acquire knowledge, and then cultivate students' innovative consciousness and ability.