Course Introduction to Natural Medicinal Chemistry I. Basic information of the course Course number: 14234076 Course category: Required courses for major Applicable major: Pharmacy Credits: 4, including 2.5 credits for theory teaching and 1.5 credits for experimental teaching Total academic hours: 88, including 40 theoretical hours and 48 experimental hours Prerequisite: Inorganic chemistry, organic chemistry, Chromatography and spectral Analysis, Medicinal Botany, pharmacognostics Setting unit: Medical College of Yangzhou University II. Course content and teaching objectives According to the training objectives and learning characteristics of undergraduate students majoring in pharmacy, the teaching objective of this course is to enable students to master the relevant theories of natural pharmaceutical chemistry, the structure types, physical and chemical properties, extraction, separation, purification and detection methods of important natural physiological active ingredients through course learning. To master the physical and spectral methods for the determination of the molecular structure of main types of natural compounds; To understand the structure-activity relationship of important natural physiologically active components; To know the physiological activities of the main types of natural compounds, and to know the latest research progress of the main types of natural compounds. Natural Medicinal Chemistry is a course that emphasizes both theory and experiment. The experimental content should include important natural pharmaceutical components, such as anthraquinones, flavonoids, terpenoids, alkaloids, etc. The main content of the experiment was extraction and separation, supplemented by identification. Several typical extraction and separation methods should be selected, and several monomer components should be separated from each raw material, and certain purity should be achieved. The identification methods include physical, chemical and chromatographic methods. The study of this course will lay a solid foundation for the study of follow-up courses and the production and research of traditional Chinese medicine and natural medicine in the future, and serve for inheriting and developing the cause of Chinese medicine and realizing the modernization of Chinese medicine. III. Basic requirements for teaching methods, practical links and students' independent learning The use of multimedia teaching methods, "heuristic" teaching principles, diversified teaching methods, the combination of teaching and discussion, strengthen exercises and classroom discussion, practical Chinese medicine and natural medicine application examples, can stimulate students' interest. Experimental course emphasizes the training of basic hands-on ability, teaching students in accordance with their aptitude, combining experimental operation with theoretical guidance. Students are required to have the ability to learn independently, cultivate professional thinking concepts and adapt to the requirements of the new era. Especially in the era of big data and health, the new requirements for talent training are put forward, and the ability to apply professional knowledge and related skills to innovation and entrepreneurship is cultivated. Ⅳ. Assessment method and evaluation of academic performance Course assessment: examination; Grade assessment: Test score (70%) + lab score (20%) + usual performance (10%) (including class attendance, performance in questioning and homework). V. Introduction to the teaching team Theory teaching and experimental teaching this course shall be the responsibility of the two teachers. Dr Chang-shui Yang will give lectures and guide in theoretical and experimental teaching contents, who finished his Ph.D. in China pharmaceutical university, the major is Chinese medicine. He specializes in the discovery of novel structural active components from traditional Chinese medicine and natural plants, have special thinking of application of traditional Chinese medicine teaching and modern concepts of pharmacy, can grasp the latest scientific and technological information combined with this course in order to improve the professional thinking and practical motivation ability of pharmaceutical students. Ms. Hongyan Yu is mainly responsible for experiment preparation and laboratory management, coordinating and solving the problems of instruments, materials and reagents in the course of experiment, and comprehensively serving the teaching of experiment course. 《天然药物化学》课程简介 （Natural Medicinal Chemistry） 一、课程基本信息 课程编号：14234076 课程类别：专业必修课 适用专业：药学专业 学 分：4，其中理论教学2.5学分，实验教学1.5学分 总 学 时：64，其中理论学时：40学时, 实验学时:48 先修课程：无机化学、有机化学、色谱与光谱分析、药用植物学、生药学 开课单位：扬州大学医学院 二、课程内容与教学目标 根据药学专业本科生培养目标及学习特点，本课程教学目标是使学生通过课程学习，掌握天然药物化学的相关理论、重要天然生理活性成分的结构类型、理化性质、提取分离、纯化及检识方法；掌握主要类型天然化合物分子结构测定的物理方法和波谱学方法；理解重要天然生理活性成分的构效关系，了解各主要类型天然化合物的生理活性，了解主要类型天然化合物研究的最新进展。天然药物化学是一门理论和实验并重的课程，实验内容应包括重要的天然药物成分类型，如蒽醌、黄酮、萜类、生物碱等。实验内容以提取分离为主，检识鉴定为辅。应选择几种较为典型的提取分离方法，对每种药材原料要求分离得到几种单体成分，并达到一定纯度。检识鉴定方法应包括物理、化学和色谱方法。通过学习此课程，为后续课程的学习以及将来从事中药与天然药物的生产和研究工作奠定基础，能为继承和发扬祖国中药事业和实现中药现代化服务。 三、对教学方式、实践环节、学生自主学习的基本要求 采用多媒体教学手段，“启发式”的教学原则，多样化的教学方法，讲授和讨论相结合，加强习题课和课堂讨论，切合实际的中药及天然药物应用实例，能够激发学生兴趣；实验课强调基本动手能力锻炼，因材施教，实验操作与理论指导相结合。对学生要求是要具备自主学习的能力，培养专业思维理念和适应新时代要求，特别是当下大数据大健康时代下，对人才培养提出的新要求，培养应用专业知识和相关技能进行创新创业的能力。 四、考核方式与学习成绩评定 课程考核方式：考试；成绩评定：考试成绩（70%）+ 实验成绩(20%) + 平时成绩(10%)（包括上课出勤、提问表现和作业上交情况等）。 五、教学团队简介 本课程理论教学与实验教学由两名教师负责，理论与实验教学内容由杨长水博士进行主讲与指导，其博士毕业于中国药科大学，本硕博专业均是中药学，专长是从中药与天然植物中发现新颖结构活性成分，具备应用中医药专业思维和现代大药学理念进行课程教学，把握最新科技信息与本课程相结合，提升药学学生专业思维和实践动力能力。于红艳老师主要负责实验准备和实验室管理，协调和解决实验课过程中出现的仪器与材料试剂问题，全面服务好实验课程教学。